ยาฆ่าเชื้อ Augmentin ชนิดเม็ด แบบแผง 10 เม็ด

Augmentin is an oral antibacterial combination medication that contains amoxicillin and clavulanate potassium, which is a beta-lactamase inhibitor[2][5]. Amoxicillin is derived from the penicillin nucleus and clavulanate potassium is produced by fermentation, possessing the ability to inactivate certain beta-lactamases by blocking their active sites[2][5]. The molecular formula for amoxicillin is C16H19N3O5S•3H2O, and for clavulanate potassium, it is C8H8KNO5[2][5].

 

### Description and Composition

- **Amoxicillin**: Analog of ampicillin, with the molecular weight of 419.46

- **Clavulanate Potassium**: Beta-lactam structurally related to penicillins, with the molecular weight of 237.25

- **Inactive Ingredients**: Vary depending on the formulation, including colloidal silicon dioxide, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, sodium starch glycolate, and titanium dioxide[2][5]

 

### Dosage Forms

- **Tablets**: Available in various strengths like 250 mg/125 mg, 500 mg/125 mg, and 875 mg/125 mg

- **Powder for Oral Suspension**: Available in different concentrations like 125 mg/31.25 mg per 5 mL and 200 mg/28.5 mg per 5 mL[2][5]

 

### Clinical Pharmacology

- **Mechanism of Action**: Augmentin is an antibacterial drug, with amoxicillin and clavulanate potassium working together to combat bacterial infections[3][5]

 

Augmentin should be used to treat or prevent infections caused by bacteria, and its effectiveness relies on maintaining the appropriate dosage and treatment duration to reduce the development of drug-resistant bacteria[3].

 

Citations:

[1] https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/050564s051lbl.pdf

[2] https://www.drugs.com/pro/augmentin.html

[3] https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/050575s037550597s044050725s025050726s019lbl.pdf

[4] https://www.cancer.gov/publications/dictionaries/cancer-terms/def/augmentin

[5] https://www.rxlist.com/augmentin-drug.htm